Unable to cope with a recent personal tragedy, LA's top celebrity shrink turns into a pothead with no concern for his appearance and a creeping sense of his inability to help his patients.

A fading celebrity decides to use a black market drug, a cell-replicating substance that temporarily creates a younger, better version of herself.

Theresa, a haunted young woman spiraling in the wake of profound loss, is torn between her fractured emotional state and the reality-altering effects of a potent cannabinoid drug.

Michaela, an epileptic, enrolls in college to study education. She goes off her medication and soon begins hearing voices and seeing apparitions that tell her to avoid religious objects, although she is devoutly Roman Catholic. One priest scoffs at the idea that Michaela could be possessed by demons, but a younger pastor arranges an exorcism for the young woman.

Undercover cop Jim Raynor is a seasoned veteran. His partner, Kristen Cates, is lacking in experience, but he thinks she's tough enough to work his next case with him: a deep cover assignment to bring down the notoriously hard-to-capture drug lord Gaines. While their relationship turns romantic during the assignment, they also turn into junkies, and will have to battle their own addictions if they want to bring down Gaines once and for all.

Heroin addict Mark Renton stumbles through bad ideas and sobriety attempts with his unreliable friends --Sick Boy, Begbie, Spud and Tommy. He also has an underage girlfriend, Diane, along for the ride. After cleaning up and moving from Edinburgh to London, Mark finds he can't escape the life he left behind as Begbie and Sick Boy come knocking.

A poet falls in love with an art student, who gravitates to his bohemian lifestyle — and his love of heroin. Hooked as much on one another as they are on the drug, their relationship alternates between states of oblivion, self-destruction, and despair.

A student gets his senses enhanced by an experimental drug. But abuse is not an option.

The alienating and repetitive life of a group of heroin junkies in 1980s Rome.

After his wife leaves him, a disillusioned director dives into the drug scene, trying anything his friend suggests.

During the 1980s, a failed stand-up comedian is driven insane and turns to a life of crime and chaos in Gotham City while becoming an infamous psychopathic crime figure.

In need of creative inspiration, a professionally stagnant and hard-partying Los Angeles artist recklessly indulges in a series of drug binges. As the narcotics fly out of control, so does her newfound and inexplicable, yet unquenchable, craving for blood.

Three stories about the world of opioids collide: a drug trafficker arranges a multi-cartel Fentanyl smuggling operation between Canada and the U.S., an architect recovering from an OxyContin addiction tracks down the truth behind her son's involvement with narcotics, and a university professor battles unexpected revelations about his research employer, a drug company with deep government influence bringing a new "non-addictive" painkiller to market.

An undercover cop in a not-too-distant future becomes involved with a dangerous new drug and begins to lose his own identity as a result.

An exploration of the United States of America's war on drugs from multiple perspectives. For the new head of the Office of National Drug Control Policy, the war becomes personal when he discovers his well-educated daughter is abusing cocaine within their comfortable suburban home. In Mexico, a flawed, but noble policeman agrees to testify against a powerful general in league with a cartel, and in San Diego, a drug kingpin's sheltered trophy wife must learn her husband's ruthless business after he is arrested, endangering her luxurious lifestyle.

A gallerist risks her family and flourishing career when she enters into an affair with a talented painter and slowly loses control of her life.

Over the course of three days Ross, a college dropout addicted to crystal-meth, encounters a variety of oddball folks - including a stripper named Nikki and her boyfriend, the local meth producer, The Cook - but all he really wants to do is hook up with his old girlfriend, Amy.

Two men wake up to find themselves shackled in a grimy, abandoned bathroom. As they struggle to comprehend their predicament, they discover a disturbing tape left behind by the sadistic mastermind known as Jigsaw. With a chilling voice and cryptic instructions, Jigsaw informs them that they must partake in a gruesome game in order to secure their freedom.

John LeTour is a recovering drug user who suffers insomnia and still deals to a high-end New York clientele, even though he’s trying to move on from the business. John’s professional midlife crisis becomes something more acute — and dangerous — when he re-encounters an old flame while a string of seemingly drug-related murders rocks the city.

Sweet suburban teen Amanda is introduced by her new friends to prescription drug-sharing, but the recreational fun soon leads her to a life-altering heroin addiction.

A young heroin addict roams the streets of New York to panhandle and get her next fix, while her unstable boyfriend drifts in and out of her life at random.

A recovering gambling addict attempts to reconcile with his family and friends but finds trouble and temptation when caught between feelings for his ex-wife and her dangerous hoodlum boyfriend.

In Los Angeles at the turn of the 1970s, drug-fueled detective Larry "Doc" Sportello investigates the disappearance of an ex-girlfriend.

A young drug-addled writer approaching the bottom of his descent submits to two months of agonizing detox at a treatment center in Minnesota.

A bigoted junkie cop suffering from borderline personality disorder and drug addiction manipulates and hallucinates his way in a bid to secure promotion.

Juggling increasing career success and a growing heroin habit, a television comedy writer attempts to go down a path of improvement.

A New York film director, working on his latest movie in Los Angeles, begins to reflect the actions in his movie and real life, especially when he begins an affair with the lead actress.

Helene, a pill-addicted anesthesiologist, is mourning the death of her boyfriend when, through a car accident she causes, she chances to meet the lethargic Gilles, a young man who lives for free at his mother's hotel. Gilles pursues Helene romantically, and she eventually softens up. Gilles, however, is also devoted to Bernard, a petty crook who revels in mugging gay men. All three struggle with relationships that seem to be going nowhere.

Paul Rivers, an ailing mathematician lovelessly married to an English émigré; Christina Peck, an upper-middle-class suburban housewife and mother of two girls; and Jack Jordan, a born-again ex-con, are brought together by a terrible accident that changes their lives.

A lawyer finds himself in far over his head when he attempts to get involved in drug trafficking.

Dr. Malcolm Sayer, a shy research physician, uses an experimental drug to "awaken" the catatonic victims of a rare disease. Leonard is the first patient to receive the controversial treatment. His awakening, filled with awe and enthusiasm, proves a rebirth for Sayer too, as the exuberant patient reveals life's simple but unutterably sweet pleasures to the introverted doctor.

This movie portrays the drug scene in Berlin in the 70s, following tape recordings of Christiane F. 14 years old Christiane lives with her mother and little sister in a typical multi-storey apartment building in Berlin. She's fascinated by the 'Sound', a new disco with most modern equipment. Although she's legally too young, she asks a friend to take her. There she meets Detlef, who's in a clique where everybody's on drugs. Step by step she gets drawn deeper into the scene.

José Sirgado is a low-budget filmmaker whose heroin addiction distorts his perspective of the real world. Although he is a depressed and unstable individual, his mood improves when he receives the mysterious films of Pedro, with whom he shares his passion for cinema.

After suffering a brutal defeat and being told he can no longer fight, 37-year-old, scar-ridden prizefighter Louis 'Mountain' Rivera struggles to find a new direction in life

A stark portrayal of life among a group of heroin addicts who hang out in Needle Park in New York City. Played against this setting is a low-key love story between Bobby, a young addict and small-time hustler, and Helen, a homeless girl who finds in her relationship with Bobby the stability she craves.

A theater director struggles with his work, and the women in his life, as he attempts to create a life-size replica of New York inside a warehouse as part of his new play.

A young drug dealer watches as his high-rolling life is dismantled in the wake of his cousin's murder, which sees his best friend arrested for the crime.

Sam Ellis is a man on the rise — a hot-shot federal prosecutor on the cusp of a bright political future. But what was meant to be a one-time experience with an escort turns into a growing addiction — a new demon threatening to destroy his life, family, and career.

A German student, Stefan, now finished with his studies, hitchhikes to Paris. There he meets a free-spirited American girl, Estelle, who he follows to Ibiza. The two begin a sad and dark path into heroin addiction.

Two gangsters seek revenge on the state jail worker who during their stay at a youth prison sexually abused them. A sensational court hearing takes place to charge him for the crimes.

New York City English professor Axel Freed outwardly seems like an upstanding citizen. But privately Freed is in the clutches of a severe gambling addiction that threatens to destroy him.

On the gritty streets of LA, the destinies of four people desperate for connection and redemption are about to collide.

Six people, each of them is on the road to self-destruction. They wake up in cells in a surreal facility, without knowing how they got there or why.

John 'Breacher' Wharton leads an elite DEA task force that takes on the world's deadliest drug cartels. When the team successfully executes a high-stakes raid on a cartel safe house, they think their work is done – until, one-by-one, the team members mysteriously start to be eliminated. As the body count rises, everyone is a suspect.

A young man turns from drug addiction and petty crime to a life redeemed by a discovery of compassion.

In New York City in the days following the events of 9/11, Monty Brogan is a convicted drug dealer about to start a seven-year prison sentence, and his final hours of freedom are devoted to hanging out with his closest buddies and trying to prepare his girlfriend for his extended absence.

Cobb, a skilled thief who commits corporate espionage by infiltrating the subconscious of his targets is offered a chance to regain his old life as payment for a task considered to be impossible: "inception", the implantation of another person's idea into a target's subconscious.

A young nurse, Alma, is put in charge of Elisabeth Vogler: an actress who is seemingly healthy in all respects, but will not talk. As they spend time together, Alma speaks to Elisabeth constantly, never receiving any answer.

Stripped of his medical license after performing an operation while high on amphetamines, famed LA surgeon Dr Eugene Sands abandons his former life only to find himself crossing paths with Raymond Blossom, an infamous counterfeiter. Employed as a "gun-shot doctor" when Raymond's associates cannot risk visiting a hospital, Eugene is lured deep into the criminal world and becomes entangled with his boss's girlfriend.

Four corrupted fascist libertines round up 9 teenage boys and girls and subject them to 120 days of sadistic physical, mental and sexual torture.

In order to diagnose the psychic traumas suffered by his patients, Dr. Paul Novotny gets young Alex Gardner to enter their dreams.

A college freshman returns to Los Angeles for Christmas at his ex-girlfriend's request, but discovers that his former best friend has an out-of-control drug habit.

A lawyer who is a drug addict fights a medical-supplies corporation in court while battling his personal demons.

Utah and his girlfriend Opal, are drug addicts living on the streets in rural Ohio. After getting recruited by body broker Wood and offered treatment in Los Angeles, Wood takes Utah under his wing and introduces him to treatment center mogul Vin. Wood and Vin bring Utah in on their lucrative and illegal dealings, where saving lives comes second to the bottom line.

Blonde Betty Elms has only just arrived in Hollywood to become a movie star when she meets an enigmatic brunette with amnesia. Meanwhile, as the two set off to solve the second woman's identity, filmmaker Adam Kesher runs into ominous trouble while casting his latest project.

After a friend overdoses, Spoon and Stretch decide to kick their drug habits and attempt to enroll in a government detox program. Their efforts are hampered by seemingly endless red tape, as they are shuffled from one office to another while being chased by drug dealers and the police.

After striking it rich on a large gold strike, a prospector retires to the quiet life on a Caribbean island but ends up coping with an alcoholic wife, a headstrong daughter, and Miami mobsters who want to build a casino.

In the hope of a big score, two junkie couples team up to commit various drug robberies which go disastrously wrong, leading to dissent, violence, and murder.

Commercial airline pilot Whip Whitaker has a problem with drugs and alcohol, though so far he's managed to complete his flights safely. His luck runs out when a disastrous mechanical malfunction sends his plane hurtling toward the ground. Whip pulls off a miraculous crash-landing that results in only six lives lost. Shaken to the core, Whip vows to get sober -- but when the crash investigation exposes his addiction, he finds himself in an even worse situation.

A boy named George Jung grows up in a struggling family in the 1950's. His mother nags at her husband as he is trying to make a living for the family. It is finally revealed that George's father cannot make a living and the family goes bankrupt. George does not want the same thing to happen to him, and his friend Tuna, in the 1960's, suggests that he deal marijuana. He is a big hit in California in the 1960's, yet he goes to jail, where he finds out about the wonders of cocaine. As a result, when released, he gets rich by bringing cocaine to America. However, he soon pays the price.

A sex-addicted con-man pays for his mother's hospital bills by playing on the sympathies of those who rescue him from choking to death.

After murdering his daughter's drug-dealing boyfriend, a wealthy ad executive stumbles into a bar and strikes up an uneasy alliance with Joe Curran, a drunken bigot with a bloodlust who works at a local factory.

Tough narcotics detective 'Popeye' Doyle is in hot pursuit of a suave French drug dealer who may be the key to a huge heroin-smuggling operation.

Medical student Ted Grey graduates at the top of his class and quickly joins an elite pathology program, whose top students invite him into their circle. There he uncovers a gruesome secret: They play a game in which one tries to commit the perfect, undetectable murder, then the others compete to determine the victim's cause of death.

Following an unexpected tragedy, child psychologist Malcolm Crowe meets a nine year old boy named Cole Sear, who is hiding a dark secret.

When a drug heist swerves lethally out of control, a jaded cop fights his way through a corrupt city's criminal underworld to save a politician's son.

An ambitious carnival man with a talent for manipulating people with a few well-chosen words hooks up with a female psychologist who is even more dangerous than he is.

A ticking-time-bomb insomniac and a slippery soap salesman channel primal male aggression into a shocking new form of therapy. Their concept catches on, with underground "fight clubs" forming in every town, until an eccentric gets in the way and ignites an out-of-control spiral toward oblivion.

A small, seemingly innocuous plastic reel of film leads surveillance specialist Tom Welles down an increasingly dark and frightening path. With the help of the streetwise Max, he relentlessly follows a bizarre trail of evidence to determine the fate of a complete stranger. As his work turns into obsession, he drifts farther and farther away from his wife, family and simple life as a small-town PI.

A drug pusher grows increasingly desperate after a botched deal leaves him with a large debt to a ruthless drug lord.

The daughter of jazz pianist Joe Albany witnesses her beloved father's struggle -- and failure -- to kick his heroin habit.

Undercover Las Vegas police officer Vincent Downs, who has a lot of enemies, is caught in a high stakes web of corrupt cops and the mob-controlled casino underground. When a heist goes wrong, a crew of homicidal gangsters kidnap Downs’ teenage son T. In one sleepless night, Downs will have to rescue his son, evade an internal affairs investigation, and bring the kidnappers to justice.

The life of a woman is transformed after she is diagnosed with a terminal disease, fired from her job and abandoned by her boyfriend. Given two months to live, she throws caution to the wind to pursue her dreams.

While investigating a young nun's rape, a corrupt New York City police detective, with a serious drug and gambling addiction, tries to change his ways and find forgiveness.

In Las Vegas, two best friends--a casino executive and a Mafia enforcer--compete for a gambling empire and a fast-living, fast-loving socialite.

Brian comes under the addictive spell of a parasite with the ability to induce euphoric hallucinations in its hosts.

Agnes and her two sisters struggle through a day in a home overrun by gamblers, thieves, and johns.

Gambling fever -- along with a brutal bookie -- leads three crooked cops into a double-dealing scheme that lands them in hot water way over their heads.

When the trail goes cold on a murder investigation of a policeman, an undercover narcotics officer is lured back to the force to help solve the case.

Thomas is a drug addict. In an effort to put an end to his habit, he joins a community of former addicts who live isolated in the mountains and use prayer as a way to cure themselves.

After the death of his girlfriend's daughter from a drug overdose, Paul Kersey takes on the local drug cartel.

Vincent, a police officer, and his partner Manuel steal a large amount of cocaine from José Marciano, a ruthless crime lord who is quick to seek revenge, endangering Vincent's life, career and family.

Ken Park focuses on several teenagers and their tormented home lives. Shawn seems to be the most conventional. Tate is brimming with psychotic rage; Claude is habitually harassed by his brutish father and coddled, rather uncomfortably, by his enormously pregnant mother. Peaches looks after her devoutly religious father, but yearns for freedom. They're all rather tight, or so they claim.

In a social context deteriorated by a countrywide economic crisis, the life of several people will be turned upside down after they meet Cécile, a character who symbolizes desire.

An ambitious lawyer finds himself caught in a power struggle between a corrupt pharmaceutical executive and his firm’s senior partner. When the case takes a deadly turn, he must race to uncover the truth before he loses everything.

A family man convicted of killing an intruder must cope with life afterward in the violent penal system.

A small, wealthy family in New York City gets progressively torn apart by secrets, lies, and the theft that orchestrates all of it.

From her volatile childhood as Norma Jeane, through her rise to stardom and romantic entanglements, this reimagined fictional portrait of Hollywood legend Marilyn Monroe blurs the lines of fact and fiction to explore the widening split between her public and private selves.

Retreating from life after a tragedy, a man questions the universe by writing to Love, Time and Death. Receiving unexpected answers, he begins to see how these things interlock and how even loss can reveal moments of meaning and beauty.

After losing her job, a single mom falls into a lucrative but ultimately dangerous scheme selling prescription drugs.

A teenager stops off to see his dealer to test a new drug before heading off for a night of partying. On the way home, he picks up an injured woman, and the night takes a surreal turn.

Despite Jigsaw's death, and in order to save the lives of two of his colleagues, Lieutenant Rigg is forced to take part in a new game, which promises to test him to the limit.

After getting into a serious car accident, a TV director discovers an underground sub-culture of scarred, omnisexual car-crash victims, and he begins to use car accidents and the raw sexual energy they produce to try to rejuvenate his sex life with his wife.

Despite their differences, Celeste and Sihem quickly become inseparable. The common will to get out of drugs seals their fusional friendship. This will be as much a force as an obstacle when, transferred from the center that welcomes them, they find themselves left to themselves, to the test of the real world and its temptations. They will have to fight to finally live.

The son of a wealthy businessman finds solace in drugs and alcohol when he breaks up with his childhood love.

A social worker assigned to the care of the daughter of a single mother intervenes when the dad returns from prison and lures them into a life of crime.

A vampiric doctoral student tries to follow the philosophy of a nocturnal comrade and control her thirst for blood.

Following a childhood tragedy, Dewey Cox follows a long and winding road to music stardom. Dewey perseveres through changing musical styles, an addiction to nearly every drug known and bouts of uncontrollable rage.

Enforcing the law within the notoriously rough Brownsville section of the city and especially within the Van Dyke housing projects is the NYPD's sixty-fifth precinct. Three police officers struggle with the sometimes fine line between right and wrong.