After his wife leaves him, a disillusioned director dives into the drug scene, trying anything his friend suggests.

In this hidden-camera prank comedy, two best friends bond on a wild road trip to New York as they pull real people into their raunchy, raucous antics.

THE SPIRIT MOLECULE weaves an account of Dr. Rick Strassman's groundbreaking DMT research through a multifaceted approach to this intriguing hallucinogen found in the human brain and hundreds of plants, including the sacred Amazonian brew, ayahuasca. Utilizing interviews with a variety of experts to explain their thoughts and experiences with DMT, and ayahuasca, within their respective fields, and discussions with Strassman’s research volunteers, brings to life the awesome effects of this compound, and introduces us to far-reaching theories regarding its role in human consciousness.

Determined to find out the true effects of marijuana on the human body, stand-up comedian and former Stoner of the Year Doug Benson documents his experience avoiding pot for 30 days and then consuming massive amounts of the drug for 30 days. More than just an amusing story of one man's quest to get superhigh, this documentary also examines the hotly contested debate over medical marijuana use.

Raoul Duke and his attorney Dr. Gonzo drive a red convertible across the Mojave desert to Las Vegas with a suitcase full of drugs to cover a motorcycle race. As their consumption of drugs increases at an alarming rate, the stoned duo trash their hotel room and fear legal repercussions. Duke begins to drive back to L.A., but after an odd run-in with a cop, he returns to Sin City and continues his wild drug binge.

A group of American teens comes to Ireland to visit a friend who takes them on a camping trip in search of the local, fabled magic mushrooms. When the psychedelics start taking hold, the panicked friends are attacked by ghostly creatures; but how can they determine whether what they are experiencing is reality or hallucination?

A pharmaceutical scientist creates a pill that makes people remember their happiest memory, and although it's successful, it has unfortunate side effects.

Over the course of three days Ross, a college dropout addicted to crystal-meth, encounters a variety of oddball folks - including a stripper named Nikki and her boyfriend, the local meth producer, The Cook - but all he really wants to do is hook up with his old girlfriend, Amy.

Jamie is a boorish, insensitive American twentysomething traveling in Chile, who somehow manages to create chaos at every turn. He and his friends are planning on taking a road trip north to experience a legendary shamanistic hallucinogen called the San Pedro cactus. In a fit of drunkenness at a wild party, Jamie invites an eccentric woman—a radical spirit named Crystal Fairy—to come along.

Rattled by sudden unemployment, a Manhattan couple surveys alternative living options, ultimately deciding to experiment with living on a rural commune where free love rules.

Jay and Silent Bob embark on a cross-country mission to stop Hollywood from rebooting a film based on their comic book characters Bluntman and Chronic.

Four girlfriends take a trip to New Orleans for an annual festival and, along the way, rediscover their wild sides and strengthen the bonds of sisterhood.

A stoner and his dealer are forced to go on the run from the police after the pothead witnesses a cop commit a murder.

When Scott learns that his longtime cyber-buddy from Berlin is a gorgeous young woman, he and his friends embark on a trip across Europe.

For the past 60 years, a space-traveling smart-ass named Paul has been locked up in a top-secret military base, advising world leaders about his kind. But when he worries he’s outlived his usefulness and the dissection table is drawing uncomfortably close, Paul escapes on the first RV that passes by his compound in Area 51. Fortunately, it contains the two earthlings who are most likely to rescue and harbor an alien on the run.

When Jay and Silent Bob learn that their comic-book alter egos, Bluntman and Chronic, have been sold to Hollywood as part of a big-screen movie that leaves them out of any royalties, the pair travels to Tinseltown to sabotage the production.

A hippie radical, Huey Walker has been a fugitive for decades, accused of a crime that he may not have committed. Finally apprehended, Walker is escorted to trial by uptight 20-something FBI agent John Buckner. While the two seem to be polar opposites, it turns out that Buckner may have more in common with Walker than is initially apparent, a point that is driven home when the pair faces off against a sinister small-town sheriff.

A young man turns from drug addiction and petty crime to a life redeemed by a discovery of compassion.

One man’s journey to find meaning in Bill Murray’s many unexpected adventures with everyday people, rare and never-before seen footage of the comedic icon participating in stories previously presumed to be urban legend.

After a shallow womanizer refuses a mysterious homeless woman's request for a kiss, he wakes up the next morning to discover he's been changed into a woman.

Nerdy accountant Harold and his irrepressible friend, Kumar, get stoned watching television and find themselves utterly bewitched by a commercial for White Castle. Convinced there must be one nearby, the two set out on a late-night odyssey that takes them deep into New Jersey. Somehow, the boys manage to run afoul of rednecks, cops and even a car-stealing Neil Patrick Harris before getting anywhere near their beloved sliders.

The escaped mental patient and delinquent John W. Burns Jr. replaces Dr. Maitlin on a radio show, saying he's the psychiatrist Lawrence Baird.

Carl Fredricksen spent his entire life dreaming of exploring the globe and experiencing life to its fullest. But at age 78, life seems to have passed him by, until a twist of fate (and a persistent 8-year old Wilderness Explorer named Russell) gives him a new lease on life.

Three lovable party buds try to bail their friend out of jail. But just when the guys have mastered a plan, everything comes dangerously close to going up in smoke.

When Earth astronaut Capt. Chuck Baker arrives on Planet 51 -- a world reminiscent of American suburbia circa 1950 -- he tries to avoid capture, recover his spaceship and make it home safely, all with the help of an empathetic little green being.

Straight-laced nerd Alistair moves into a college dorm with hardcore marijuana users, who order an old giant bong that proves to have strange magical powers, which sends people to a bizarre drugged-out alternate realm from which there is no easy escape.

An intimate look at the Woodstock Music & Art Festival held in Bethel, NY in 1969, from preparation through cleanup, with historic access to insiders, blistering concert footage, and portraits of the concertgoers; negative and positive aspects are shown, from drug use by performers to naked fans sliding in the mud, from the collapse of the fences by the unexpected hordes to the surreal arrival of National Guard helicopters with food and medical assistance for the impromptu city of 500,000.

A road trip comedy about three friends who travel across the country in a Wiener Wagon to beat up a popular daytime talk show therapist.

One day at work, unsuccessful puppeteer Craig finds a portal into the head of actor John Malkovich. The portal soon becomes a passion for anybody who enters its mad and controlling world of overtaking another human body.

A surreal triptych adapted by "Trainspotting" author Irvine Welsh from his acclaimed collection of short stories. Combining a vicious sense of humor with hard-talking drama, the film reaches into the hearts and minds of the chemical generation, casting a dark and unholy light into the hidden corners of the human psyche.

A research scientist explores the boundaries and frontiers of consciousness. Using sensory deprivation and hallucinogenic mixtures from native American shamans, he explores these altered states of consciousness and finds that memory, time, and perhaps reality itself are states of mind.

Wyatt and Billy, two Harley-riding hippies, complete a drug deal in Southern California and decide to travel cross-country in search of spiritual truth.

When Steve Coogan is asked by The Observer to tour the country's finest restaurants, he envisions it as the perfect getaway with his beautiful girlfriend. But, when she backs out on him, he has no one to accompany him but his best friend and source of eternal aggravation, Rob Brydon.

A spoof on many horror movie series. Ending his shift at the video rental, Stan's picked up by his BFF and 2 cute girls, all going to a Halloween party. Will they even get there?

A straight-laced pharmacist's uneventful life spirals out of control when he starts an affair with a trophy wife customer who takes him on a joyride involving sex, drugs and possibly murder.

Two mental patients with opposite personalities ditch their Tuscan hospital and embark on an unpredictable exploration of the real world.

A woman turns to prescription medication as a way of handling her anxiety concerning her husband's upcoming release from prison.

When two jobless friends discover a hidden weed bible and the ultimate bud, they think that they’ve got it made…with 'seed' money to start a new snack delivery app. But, when nearly all of their stash and weed bible are stolen, the two potpreneurs set off on an outrageous, mind-bending adventure through Atlanta to find them. Stoned with supernatural powers, they search 'high' and low, stopping at nothing to recover their ticket to starting a legit business.

A prisoner in a state-of-the-art penitentiary begins to question the purpose of the emotion-controlling drugs he's testing for a pharmaceutical genius.

Theresa, a haunted young woman spiraling in the wake of profound loss, is torn between her fractured emotional state and the reality-altering effects of a potent cannabinoid drug.

Moronic best friends get themselves locked inside the Bio-Dome, a science experiment, along with a group of environmental scientists for one year.

Two stoners wake up after a night of partying and cannot remember where they parked their car.

In a hypercompetitive world, drugs like Adderall offer students, athletes, coders and others a way to do more -- faster and better. But at what cost?

After spending two decades in England, Bill Bryson returns to the U.S., where he decides the best way to connect with his homeland is to hike the Appalachian Trail with one of his oldest friends.

An 18th birthday mushroom trip brings free-spirited Elliott face-to-face with her wisecracking 39-year-old self. But when Elliott’s "old ass" starts handing out warnings about what her younger self should and shouldn't do, Elliott realizes she has to rethink everything about family, love, and what's becoming a transformative summer.

A supermarket clerk decides to step in for an absent drug dealer, setting off an explosive, comedic chain of events.

Does infinity exist? Can we experience the Infinite? In an animated film (created by artists from 10 countries) the world's most cutting-edge scientists and mathematicians go in search of the infinite and its mind-bending implications for the universe. Eminent mathematicians, particle physicists and cosmologists dive into infinity and its mind-bending implications for the universe.

While on a coach tour, The Beatles and a few dozen friends experience strange happenings caused by magicians.

Four stoners, five vegans, three mobsters, four hunters and a million reasons to free one junkie elephant.

Multi-platinum rap superstars Redman and Method Man star as Jamal and Silas, two regular guys who smoke something magical, ace their college entrance exams and wind up at Harvard. Ivy League ways are strange but Silas and Jamal take it in a stride -- until their supply of supernatural smoke runs dry. That's when they have to start living by their wits and rely on their natural resources to make the grade.

An exposé of comic proportions that only Chris Rock could pull off, GOOD HAIR visits beauty salons and hairstyling battles, scientific laboratories and Indian temples to explore the way hairstyles impact the activities, pocketbooks, sexual relationships, and self-esteem of the black community.

A high school valedictorian who gets baked with the local stoner finds himself the subject of a drug test. The situation causes him to concoct an ambitious plan to get his entire graduating class to face the same fate, and fail.

“Half Baked” meets “Superbad” in this hilarious comedy following two young losers whose lives are unexpectedly turned upside down when they find some marijuana that has aphrodisiacal side effects. After deciding to use the wacky weed to their advantage, the guys meet an array of pot-loving beauties.

Perennially stoned Cheech and Chong tear through the city of Los Angeles, causing trouble wherever they go. After Cheech loses his job, the two pot enthusiasts head to the welfare offices where Cheech's girlfriend, Donna, works. Instead of collecting unemployment, they find themselves thrown back on the streets, searching for a way to earn new income. But when Cheech's cousin, "Red" Mendoza, arrives, things get even crazier.

Join uptight David Starsky and laid-back Ken "Hutch" Hutchinson as they're paired for the first time as undercover cops. The new partners must overcome their differences to solve an important case with help from street informant Huggy Bear and persuasive criminal Reese Feldman.

Based on real near-death experiences, the afterlife is explored with the guidance of New York Times bestselling authors, medical experts, scientists and survivors who shed a light on what awaits us.

When Altan swipes prescription drugs from his brother Nuri's pharmacy, they soon find themselves on a dangerous but funny road trip to get rid of the stuff and escape the mafiosi Altan tried to double-cross. Along the way, the brother who are compete opposites finally bond.

While attending a party at James Franco's house, Seth Rogen, Jay Baruchel and many other celebrities are faced with the apocalypse.

A group of friends head to the land of oaky Chardonnays and big, bold Cabernet Sauvignons for one member of the squad’s 50th birthday party.

Like the original film, the sequel is set in a near future where all drinking and drugs are banned except for on one glorious day known as The Binge. This year, that day happens to miraculously land on Christmas.

Angela and Jessie are best friends intent on taking a wild beach trip, but when their roommate loses all of their money in a drug scam, the girls -- blissfully stoned -- go to increasingly daring and absurd lengths to get it back.

A no-nonsense cop has a flair for fashion and a celebrity takes revenge on the paparazzi in a collection of comedic sketches.

When indie comic character Pepe the Frog becomes an unwitting icon of hate, his creator, artist Matt Furie, fights to bring Pepe back from the darkness and navigate America's cultural divide.

It's 1983, and hopeless junkie Dick gets an unwelcome visit from the past - his seriously sleazy former cellmate, Bug, to be precise. Bug requires a crash course in the 80s: different music, different drugs, and machines in walls that dispense money. The latter development gives Dick an idea.

One-man armies, meet-cutes, casual strolls away from huge explosions — stars and industry insiders toast and roast these cinematic chestnuts and more.

Best friends Alice and Darlene take a trip to Thailand after graduating high school. In Thailand, they meet a captivating Australian man, who calls himself Nick Parks. Darlene is particularly smitten with Nick and convinces Alice to take Nick up on his offer to treat the two of them to what amounts to a day trip to Hong Kong. In the airport, the girls are seized by the police and shocked to discover that one of their bags contains heroin.

When Will Ferrell's good friend Harper comes out as a trans woman, they take a road trip to bond and reintroduce Harper to the country as her true self.

Jane, a struggling but perpetually stoned actress, has a busy day ahead. She has several important tasks on her list, including buying more marijuana. Even though she already has a good start on the day's planned drug use, she eats her roommate's pot-laced cupcakes and embarks on a series of misadventures all over Los Angeles.

A day in the life of two best friends, a drug dealer, and a store manager collide at a hip-hop concert in the Inland Empire.

The adventures of a group of Texas teens on their last day of school in 1976, centering on student Randall Floyd, who moves easily among stoners, jocks and geeks. Floyd is a star athlete, but he also likes smoking weed, which presents a conundrum when his football coach demands he sign a "no drugs" pledge.

A group of friends on holiday on an island experiment with a new designer drug that makes them lose their ability to control their urges.

A mockumentary that chronicles the prevalence of doping in the world of professional cycling.

A romantic comedy that brings together three disparate characters who are learning to face a challenging and often confusing world as they struggle together against a common demon—sex addiction.

Clark Griswold is on a quest to take his family to the Walley World theme park for a vacation, but things don't go exactly as planned.

A comedy that follows the chaos that ensues when a meteor hits the Earth carrying alien life forms that give new meaning to the term "survival of the fittest." David Duchovny, Orlando Jones, Seann William Scott, and Julianne Moore are the only people standing between the aliens and world domination... which could be bad news for the Earth.

A high school girl encounters a variety of kookie characters and humorous sexual situations while searching for the meaning of life.

Cast, crew and fans explore the 'Back to the Future' time-travel trilogy's resonance throughout our culture—30 years after Marty McFly went back in time.

Amiable slackers Bill and Ted are once again roped into a fantastical adventure when De Nomolos, a villain from the future, sends evil robot duplicates of the two lads to terminate and replace them. The robot doubles actually succeed in killing Bill and Ted, but the two are determined to escape the afterlife, challenging the Grim Reaper to a series of games in order to return to the land of the living.

Barry is a drug-addled, abusive bastard who - after yet another bender - is abducted by aliens. Barry takes a backseat as an alien visitor assumes control of his body and takes it for a joyride through Cape Town. What follows is an onslaught of drugs, sex, and violence as our alien tourist enters the weird and wonderful world of humankind.

Four animal friends get a taste of the wild life when they break out of captivity at the Central Park Zoo and wash ashore on the island of Madagascar.

A young girl named June with a big imagination makes an incredible discovery -- the amusement park of her dreams has come to life. Filled with the world's wildest rides operated by fun-loving animals, the excitement never ends. But when trouble hits, June and her misfit team of furry friends begin an unforgettable journey to save the park.

Malcolm is carefully surviving life in a tough neighborhood in Los Angeles while juggling college applications, academic interviews, and the SAT. A chance invitation to an underground party leads him into an adventure that could allow him to go from being a geek, to being dope, to ultimately being himself.

Nice Dreams - it rhymes with ice creams. And that's what Cheech and Chong are selling in this thoroughly wacky comedy. The outrageous, permanently spaced-out duo sells enough of their "specially mixed" ice cream to take the cash and realize their fondest dreams: new guitars, islands in the sun and beautiful women. But, of course, not everything goes as planned. While celebrating their wealth in a new wave Chinese restaurant, Cheech meets his long-lost love Donna, and promptly escorts her to her posh penthouse. He soon learns, however, that Donna's boyfriend, an ex-con named Animal, is on his way to her boudoir. Meanwhile, Chong has unwittingly exchanged all their money for a worthless bank check - and the only way to get it back is to escape into a nearby insane asylum.

An undercover cop in a not-too-distant future becomes involved with a dangerous new drug and begins to lose his own identity as a result.

An uptight documentary filmmaker and his wife find their lives loosened up a bit after befriending a free-spirited younger couple.

Dexter and Royce, two stoners in the small town of Weedsville, attempt to cover up the overdose of Royce's girlfriend Matilda. What leads from an old drive-in being perfect place to ditch her turns into the accidental discovery of a Satanic cult, who brings Mattie back from the dead after their ritual is botched. Along with the two's dealer Omar on their tail, how will these buddies and their slightly-off lady-on-board deal with the dangers of drug debt and demon-worshipping magic?

Nando and Erika, two young people in their twenties, meet several times without noticing. The story of the subculture of electronic music and rave parties and drugs like MDMA.

An irreverent comedy about the misadventures of Moondog, a rebellious stoner and lovable rogue who lives large.

An unemployed pot-smoking slacker and amateur drummer, Anthony Stoner ditches his strict parents and hits the road, eventually meeting kindred spirit Pedro de Pacas. While the drug-ingesting duo is soon arrested for possession of marijuana, Anthony and Pedro get released on a technicality, allowing them to continue their many misadventures and ultimately compete in a rock band contest, where they perform the raucous tune "Earache My Eye."

Four pals are stuck in a rut in adulthood: Adam has just been dumped, Lou is a hopeless party animal, Nick is a henpecked husband, and Jacob does nothing but play video games in his basement. But they get a chance to brighten their future by changing their past after a night of heavy drinking in a ski-resort hot tub results in their waking up in 1986.

It's vacation time for outdoorsy Chicago man Chet Ripley, along with his wife, Connie, and their two kids, Buck and Ben. But a serene weekend of fishing at a Wisconsin lakeside cabin gets crashed by Connie's obnoxious brother-in-law, Roman Craig, his wife, Kate, and the couple's two daughters. As the excursion wears on, the Ripleys find themselves at odds with the stuffy Craig family.

Slacker duo Beavis and Butt-Head wake to discover their TV has been stolen. Their search for a new one takes them on a clueless adventure across America, during which they manage to accidentally become America's most wanted.

An intense new marijuana strain named “Black Forest” is taking Los Angeles by storm, and Gretel’s stoner boyfriend can’t get enough. But when the old woman growing the popular drug turns out to be an evil witch, cooking and eating her wasted patrons for their youth, Gretel and her brother Hansel must save him from a gruesome death — or face the last high of their lives.

Using previously unheard audiotapes recorded shortly after John Belushi’s death, director R.J. Cutler’s documentary feature examines the too-short life of the once-in-a-generation talent who captured the hearts and funny bones of devoted audiences.

Determined to avoid another night of driving aimlessly around Torrance in the Blue Torpedo, Joe and Hubbs set out on a quest for fine chicks. Their paths soon cross with Tack, from whom they learn about a pair of foreign radical chicks hanging out near the Frankie Avalon place. Over Joe's objections, Hubbs worms Tack out of the deal, and the pair take a slow ride toward their destiny.

A woman, accidentally caught in a dark deal, turns the tables on her captors and transforms into a merciless warrior evolved beyond human logic.

An unhappy housewife gets a lift from the return of her imaginary childhood friend, Drop Dead Fred.

After a car crash sends repressed cartoonist Stu into a coma, he and the mischievous Monkeybone, his hilarious alter-ego, wake up in a wacked-out waystation for lost souls. When Monkeybone takes over Stu's body and escapes to wreak havoc on the real world, Stu has to find a way to stop him before his sister pulls the plug on reality forever!

A bright young yeti finds something he thought didn't exist—a human. News of this “smallfoot” throws the simple yeti community into an uproar over what else might be out there in the big world beyond their snowy village.