Irene lives in Rome. When her mother ask to, she go back to Rimini, her hometown, to take care of her autistic brother, Omar. She soon discover that Omar knows very well what to expect from the future, but in order to achieve his dreams, he need to be independent, which is why Irene begins a tender crash course to teach him adult life.

A mentally challenged girl proves herself to be every bit as capable as her "perfect" sister when she moves into an apartment and begins going to college.

Sam and Gray are such a well-matched pair that it is difficult to believe they are brother and sister rather than husband and wife. They both share a love of 1940s movies and dancing, and when they meet Charlie, they have something else in common: They both fall in love with her. Sam must deal with unexpected feelings of jealousy, while Gray struggles to come to terms with her sexual orientation.

Teenager David Clemens develops a hysterical fear that he will die if he comes into physical contact with another person. Perturbed, David's overbearing mother places him in a home for mentally disturbed young people, but David remains withdrawn from the other patients and his psychiatrist. Over time, however, David grows interested in 15-year-old Lisa, who suffers from multiple personalities – one who can only speak in rhyme, and the other, a mute.

A teenage girl gets diagnosed with a reproductive condition that upends her plans to have sex and propels her into exploring unusual methods to have a sex life, challenging her relationships with everyone in her life, but most importantly, herself.

Adam, a lonely man with Asperger's Syndrome, develops a relationship with his upstairs neighbor, Beth.

Sheltered by his grandparents, Luke, a young man with autism, is thrust into a world that doesn't expect anything from him. But Luke is on a quest for a job and true love. And he isn't taking no for an answer.

In a remote woodland cabin, a small town doctor discovers Nell — a beautiful young hermit woman with many secrets.

Zu, a free spirit estranged from her family, suddenly finds herself the sole guardian of her half-sister, Music, a teenager on the autism spectrum whose whole world order has been beautifully crafted by her late grandmother. The film soon challenges whether it is Zu or Music who has a better view of the world, and that love, trust, and being able to be there for each other is everything.

Kate Stone is career-focused with a brash attitude that keeps relationships at an arm's length. When her estranged brother calls asking her to baby-sit her tween niece Maddie, Kate reluctantly agrees to help. But baby-sitting overnight unexpectedly turns into a week, and Kate's life spins into chaos. As Maddie reveals stories of being bullied and of wanting to run away and be a Juggalo, the two form a unique bond.

The buttoned-down, superstitious Kay is attempting to lead a normal existence with her new boyfriend Louis. That’s until Sweetie, her rampaging, devil-may-care sister, returns home after an absence, exposing the rotten roots of their family and placing a strain on Kay and Louis’ relationship.

For twenty years, Bruno and Malik have lived in a different world—the world of autistic children and teens. In charge of two separate nonprofit organizations (The Hatch & The Shelter), they train young people from underprivileged areas to be caregivers for extreme cases that have been refused by all other institutions. It’s an exceptional partnership, outside of traditional settings, for some quite extraordinary characters.

An experiment on a simpleton turns him into a genius. When he discovers what has been done to him he struggles with whether or not what was done to him was right.

As a child, Jack believed the tender lie his parents told him, that Gio was a special being with superpowers, as in a comic book. Now that he is about to go to high school, however, Jack no longer believes that his brother is a superhero, in fact, he is almost ashamed of him, especially since he met Arianna, the first love of his life.

A young autistic museum guide lives by a strict routine — until he falls in love with his coworker and must confront a whirlwind of new, intense emotions.

On the outside, Helen has it all – a loving family and a successful career – but when her suppressed mental illness resurfaces, the world crumbles around her. Crippled by depression, Helen finds solace through her friendship with Mathilda, a kindred spirit struggling with bipolar disorder.

A mentally ill young woman finds her love in an eccentric man who models himself after Buster Keaton.

Love for the same woman causes conflict between an over-achieving blind athlete and the brother who made him that way.

A biopic of Temple Grandin, an autistic American who has become one of the leading scientists in humane livestock handling.

After a blow to the head, Abby decides she can't do it anymore. Her life just can't be only about the house, the kids and the wife. She needs more: she needs to be Eleanor.

Simon has Asperger's syndrome and doesn't like changes in his life. He lives with his big brother Sam and Sam's girlfriend Frida. When Frida can't stand having to adapt to Simon's peculiarities anymore she takes off, leaving Simon with having to find a new, perfect, girlfriend for his brother.

A love story between two savants with Asperger's syndrome, a kind of autism, whose conditions sabotage their budding relationship.

A non-verbal, autistic girl and a chatty boy are partnered on a canoeing trip. To complete their journey across an urban lake, they must both learn how the other experiences the world.

With the help of her friends, Emily moves to a remote home to take better care of her brother, Zack who is diagnosed with cerebral palsy. But what they don't know is that the house is keeping a terrifying secret that will haunt them one by one.

The story of Bea Johnson from birth to graduation as she navigates life with an intellectually disabled parent and an extended family who can't quite agree on the best way to help.

Melody Brooks, a sixth grader with cerebral palsy, has a quick wit and a sharp mind, but because she is non-verbal and uses a wheelchair, she is not given the same opportunities as her classmates. When a young educator notices her student's untapped potential and Melody starts to participate in mainstream education, Melody shows that what she has to say is more important than how she says it.

David, a struggling comedy writer fresh off from breaking up with his boyfriend, moves from New York City to Sacramento to help his sick mother. Living with his conservative father and much-younger sisters for the first time in ten years, he feels like a stranger in his childhood home. As his mother’s health declines, David frantically tries to extract meaning from this horrible experience and convince everyone (including himself) that he's "doing okay.”

A charismatic, crazy hothead transforms a family's life when she becomes the nanny of five girls.

A young autistic woman runs away from her caregiver in order to boldly go and deliver her 500-page Star Trek script to a writing competition in Hollywood. On an adventure full of laughter and tears, Wendy follows the guiding spirit of Mr. Spock on her journey into the unknown.

Just as Mike is on the heels of closing the biggest deal of his career, he's pulled away from his bachelor life in the big city to a farm in rural Ohio in order to help his recently orphaned nephews find a new home.

A young woman dealing with anorexia meets an unconventional doctor who challenges her to face her condition and embrace life.

Precocious young Harriet and her older sister Gwen live at their mother's motel in small-town New Hampshire. Harriet dreams of a life beyond her inattentive family and the stultifying town. A mentally disabled man named Ricky comes to stay at the motel, and Harriet finds him kinder and more interesting than anyone she has ever met. After tragedy strikes, Harriet and Ricky cling to each other ever more tightly.

A young MBA mistakenly interviews for the wrong job... and ends up as an Au Pair for a pair of snotty rich kids.

The "black sheep" son of a wealthy family meets a young psychiatric patient who's been raised in isolation her entire life. He takes the naive young woman home for his brother's wedding an improbable romance blooms, as she impresses everyone with her genuine, simple charms.

After returning to her childhood home, young nun Colleen finds her old room exactly how she left it: painted black and covered in goth and metal posters. Her parents are happy enough to see her, but her brother is living as a recluse in the guesthouse since returning home from the Iraq war.

A teenage con artist tricks a desperate mother into hiring her as a live-in companion for her autistic daughter.

When Ruth Matthews's husband is killed in a fall at an archaeological dig, her daughter Sally handles her father's death in a very odd manner. As Sally's condition worsens, Ruth takes her to see Jake, an expert in childhood autism. Jake attempts to bring Sally out of her mental disarray through traditional therapy methods, but Ruth takes a different route. She risks her own sanity by attempting to enter her daughter's mind and make sense of the seemingly bizarre things that Sally does, including building a wondrous house of cards

After graduating from film school, Aura returns to New York to live with her photographer mother, Siri, and her sister, Nadine, who has just finished high school. Aura is directionless and wonders where to go next in her career and her life. She takes a job in a restaurant and tries unsuccessfully to develop relationships with men, including Keith, a chef where she works, and cult Internet star Jed.

When Pete and Ellie decide to start a family, they stumble into the world of foster care adoption. They hope to take in one small child but when they meet three siblings, including a rebellious 15 year old girl, they find themselves speeding from zero to three kids overnight.

Thomas is turning 16. His dad's in the army and they've just moved to a town in New South Wales; his mom is pregnant; his older brother, Charlie, who's autistic, has his own adolescent sexual issues. Thomas finds Charlie an embarrassment in public, so when Thomas is attracted to Jackie, a girl in his swim class, Charlie presents any number of obstacles when she drops by their house, when the three of them go for a walk, and during a family birthday dinner. Can Thomas find a way to enter the world of teen romance and still be his brother's keeper, or is Charlie's disability going to prove more than Thomas can handle?

Still mourning the death of her mother a few years back, Alice McKinley finds her life seriously disrupted when her father Ben buys a store and moves her and her older brother Lester to a new town.

Traumatized since childhood by her brother's accidental death, Danika Merrick hallucinates a bank robbery and quits her job. Despite support from her three children and loving husband, Danika continues to experience unnerving visions. She seeks help from therapist Evelyn Harris but pervasive reports of violent incidents involving children make Danika fear for her own family, and she grows increasingly paranoid, worrying she may be going insane.

A woman named Emily checks into a hotel and offers the bellboy $2000 to temporarily marry her. We soon find out Emily is the caretaker of a wheelchair-bound mute named Helga, who was the childhood guardian of a pair of siblings: Miriam Webster and her half-brother, Warren, who is about to inherit the estate of their late father. Who is the mysterious Emily and what are her intentions?

Hal is a 15-year-old high-school student with a minor yet socially alienating (and painful) disability: he stutters uncontrollably. Determined to work through the problem, Hal opts for an extreme route – he joins the school debating team, which sends him on a headfirst plunge into breakneck speech competitions and offers a much-needed boost toward correcting the problem.

15-year-old Rocks fears that she and her little brother Emmanuel will be taken into care and forced apart if anyone finds out that their mother has left them. Against all odds, and with the help of her loyal friends, she evades the authorities and navigates the most defining days of her young life.

Clara and Diego, under the guidance of the psychiatrist of a day rehabilitation center for disturbed people who attend, decide to transform the treatment center into a restaurant, involving all their other companions.

Accused of murder and confined to a mental institution, Molly Hartley falls under the possession of a powerful demonic force. As she undergoes a monstrous transformation, a defrocked priest is her only hope of salvation.

Se-ha who is a physically handicapped and Dong-gu who is a mentally handicapped are not their own brothers. But while living 20 years together, the two became indispensable to each other. One day, the mother of Dong-gu suddenly visits him and acts as his guardian.

Michael is a 24-year-old who has cerebral palsy and long-term resident of the Carrigmore Residential Home for the Disabled, run by the formidable Eileen. His life is transformed when the maverick Rory O'Shea moves in.

An intimate family portrait of four hapless but resilient women and the bittersweet lessons they learn in keeping up with the hectic demands of their individual neuroses. Each of the women seeks redemption in her own haphazard way, but whatever salvation they find is illusory and short-lived.

Matteo is a young successful businessman, audacious, charming and energetic. Ettore instead, is a calm, righteous, second grade teacher always living in the shadows, still in the small town from where both come from. They’re brothers but with two very different personalities. A dramatic event will force them to live together in Rome for a few months, bringing up the opportunity to face their differences with sympathy and tenderness, in a climax of fear and euphoria.

A leukemia patient attempts to end a 20-year feud with her sister to get her bone marrow.

Having seen the double murder of his parents, autistic youth Tim Warden is sent to therapy with controversial therapist Dr. Jake Rainer. Jake tries to probe the silent child about what he saw, but he gets more details about the Wardens' household dynamics from Tim's teenage sister, Sylvie. As he spends more time with the siblings, Jake learns that the Wardens' marriage was not as perfect as it seemed, and he uncovers other new details that might help solve the crime.

Ben Cooper and his family are struggling to get a grip on household chores, school and work. So when Ben sees that a Smart House is being given away, he enters the competition as often as he can, until they eventually win the house (named Pat). After moving in, Pat's personality radically begins to change, turning the Coopers against her.

After a breakup with her boyfriend, a young woman moves in with her older brother, his wife, and their 2-year-old son.

Swiss girl Adelheid 'Heidi' is orphaned young. Aunt Detie brings her to grandpa Alp and his wife, who live isolated in the Alps since his murder charge. Heidi soon takes to the wild country, especially accompanying young goatherd Peter. Grandpa refuses to send her to school in the city, but aunt Detie returns and forces him to give in. She's sent to a posh lady in Frankfurt, where she'll be a companion for crippled daughter Clara after school hours.

Everybody has one—the sibling who is always just a little bit behind the curve when it comes to getting his life together. For sisters Liz, Miranda and Natalie, that person is their perennially upbeat brother, Ned. But as each of their lives begins to unravel, Ned's family comes to realise that Ned isn't such an idiot after all.

Struggling to provide her daughters with a safe, happy home, Sandra decides to build one - from scratch. Using all her ingenuity to make her ambitious dream a reality, Sandra draws together a community to lend a helping hand to build her house and ultimately recover her own sense of self.

Andy Goodrich's life is upended when his wife enters a rehab program, leaving him on his own with their young kids. Goodrich leans on his daughter from his first marriage, Grace, as he ultimately evolves into the father Grace never had.

A young woman, Janice, is living with her restrictive and conservative parents, who lead a dull working-class life and consider their daughter to be “misbehaving” whenever she’s trying to find her own way in life.

After getting into a car accident while drunk on the day of her sister's wedding, Gwen Cummings is given a choice between prison or a rehab center. She chooses rehab, but is extremely resistant to taking part in any of the treatment programs they have to offer, refusing to admit that she has an alcohol addiction.

At Phoenix Progressive School, students take notes lying on parlor couches and are encouraged to explore their gifts through electives like break-dancing and graphic-novel writing. In the midst of all this liberal pedagogy and budding talent, Molly Maxwell feels unexceptional, until she falls for her attractive English teacher, Ben.

When a self-destructive teenager is suspended from school and asked to look after his feisty alcoholic grandmother as a punishment, the crazy time they spend together turns his life around.

A mother, unable to confront the heartbreak of her son leaving for college, delays his departure by making him sick. Unfortunately, she goes too far.

A charming romance develops between a boy with one eye and an overweight girl, though when she loses weight after going to college, their relationship is tested in devastating ways they never dreamed would happen.

Richard and Rachel, a couple in the throes of infertility, try to maintain their marriage as they descend deeper and deeper into the insular world of assisted reproduction and domestic adoption.

Roger Greenberg, a failed musician now making a living as a carpenter in New York, returns to Los Angeles to house-sit for his brother. He's stranded there—since he doesn't drive—until his brother's assistant, Florence, comes to his rescue. She's as much a lost soul as he is, and the pair form a significant connection—giving Roger a much-needed reason to be happy.

Muriel is beautiful, free-spirited and bed-ridden since a horrific accident. Leo is a drunk middle-aged ex-boxer. Desperate for work and unqualified, he interviews for Muriel, who hires him to cook and care for her against her better judgment. Initially out of his depth, Leo slowly wins Muriel's trust. As Muriel teaches him to read, he forces her to confront the joys beyond her window.

Anna is stuck: she’s approaching 30 and has just moved back to her rural home-town, and into a shed in her mother’s backyard. She spends her time working a menial job at a local boating center and hides in the depths of her imagination, making movies with her thumbs. Irritated by her childish behavior, Anna's mother insists that she move out of her shed and on with her life. When a troubled young boy starts hanging around, the two form an unlikely bond. Through their strange yet mutually beneficial friendship, Anna slowly begins to confront her perpetual state of arrested development.

Marie Heurtin is born both blind and deaf. Sister Marguerette wins her trust and teaches her how to express herself.

With John's social life at a standstill and his ex-wife about to get remarried, a down on his luck divorcée finally meets the woman of his dreams, only to discover she has another man in her life - her son. Before long, the two are locked in a battle of wits for the woman they both love-and it appears only one man can be left standing when it's over.

Frank, a single man raising his child prodigy niece Mary, is drawn into a custody battle with his mother.

Halley is convinced true love doesn't exist based on the crazy relationships around her. Her mother is divorcing her father who is dating a younger woman Halley can't stand. Her crazed sister is planning a wedding but has second thoughts and her best friend has fallen madly in love for the first time leaving Halley to feel even more alone.

When Ruby and Rhett's parents are killed in a car accident, their carefree teenage lives are suddenly shattered. Moving to an incredible house in Malibu with the Glasses', old friends of the family, seems to be the beginning of a new life for them.

Zoey is a talented dancer whose organized life is rudely disrupted when she moves in with her new step-dad and three step-brothers, until she discovers a dog-training app that can get boys to obey her every command. But she soon learns that it isn't the cure-all she had hoped for.

An epileptic 12-year-old girl, Pippi, is hospitalized in the psychiatric ward instead of the neurological ward, due to an administration error. Out of this mistake begins the difficult journey towards being cured.

Heidi, is an eight-year-old Swiss orphan who is given by her aunt to her mountain-dwelling grandfather. She is then stolen back by her aunt from her grandfather to live in the wealthy Sesemann household in Frankfurt, Germany as a companion to Klara, a sheltered, disabled girl in a wheelchair. Heidi is unhappy but makes the best of the situation, always longing for her grandfather.

After her lousy stepfather steals her savings to buy a vicious tiger, Kelly loses all hope of going to college. But Kelly's situation worsens when a hurricane leaves her and her autistic brother boarded up in their house with the man-eating beast. This edge-of-your-seat thriller follows the gutsy heroine and her younger sibling as they struggle to outwit the ravenous predator and find a way to survive.

A flying saucer lands in the backyard of an elderly suburbanite with memory problems, who forms a bond with the scared alien inside.

A fledgling caterer, Molly Frost, is hired by Jean Harrison, the perfectionistic director of the renowned Harrison Foundation, to cater this year’s annual Christmas Gala dinner. Things get complicated when Molly falls for Jean’s nephew, Carson, 30s, a travel photographer with no desire to take over the family’s foundation… until his aunt assigns him to the task of making sure the catered dinner goes perfectly.

Handsome but backward gardener Tim Melville has a new woman in his life. She is Mary, his widowed employer, a woman who had given up on love until she had found Tim. At first they are friends. But soon they become lovers, as Mary, drawn to Tim's innocence and magnetism, begins to teach him all about life - and love.

Twins separated at birth, Camryn and Alex meet by chance for the first time on their 21st birthday and discover they're witches with the power to save their homeland of Coventry from the evil that threatens it. But when Camryn leaves Alex to face the darkness alone, will Coventry be doomed? Or will the sisters multiply their magic by standing together?

A quiet, neglected girl is sent away from her dysfunctional family to live with relatives for the summer. She blossoms in their care, but in this house where there are meant to be no secrets, she discovers one.

Paralyzed after a terrible accident, Dana struggles to regain her life and family when she encounters a malevolent ghost in her hospital room.

An absentee father and his bipolar son are forced to live together as they struggle with a recent family tragedy. The tension and anxiety boil as they live and try to cope in a tiny apartment. As time passes, they realize their shared pain is not their only source of grief, as they find the outside world is a cruel and unjust place.

When their father's will forces them to live together, siblings Nik and Tesla — and Tesla's kids — try to overcome their differences to become a family.

A woman tries to exonerate her brother's murder conviction by proving that the crime was committed by a supernatural phenomenon.

A neurotic, twice-divorced sci-fi writer moves back in with his mother to solve his personal problems.

At 2 Ela lost her ability of seeing and hearing because of a severe illness. And then she became a total disappointment of her family due to her untamed behaviors. But everything changed after an unorthodox teacher stepped into their lives to educate Ela while healing himself.

Forcibly separated from her twin brother when they are orphaned, a melancholic misfit learns how to find confidence within herself amid the clutter of misfortunes and everyday life.

Following the outbreak of a virus that wipes out the majority of the human population, a young woman documents her family's new life in quarantine and tries to protect her infected sister.

Not long after moving into her own place, Maggie finds herself with two unsolicited roommates: her recently divorced mother, Lila, and her young brother. The timing is especially bad, considering Maggie has fallen hard for an attractive woman, Kim, only hours before they move in. What could be a nonissue becomes increasingly complicated -- since Maggie's family is unaware of her sexual orientation, and Maggie is not open to sharing that information.

Undiagnosed, untreated and generally untethered schizophrenic Julien lives with his pregnant younger sister Pearl, anorexic would-be wrestler brother Chris, sympathetic grandmother, and severely depressed German father.

After being neglected by her mother, a little girl is taken in by her uncle and his transgender girlfriend, who create a loving home for her.

A young man with a bright future suffers a near-fatal accident and recreates his new life with the help of an unlikely animal friend.

When a car crash leaves Frannie immobilized, she is brushed off by everyone she can count on. With nowhere else to turn and desperate for help, she turns to an unlikely source, her ex Devon.

In college, attorney Molly Singer was the life of every party. Now, she's about to be fired because she can't leave her partying ways behind. Molly's boss, Brenda, tells Molly there's one way to save her job: re-enroll at her old alma mater, befriend Brenda's socially awkward son, Elliot, and take him from zero to campus hero.

Diagnosed with a mental illness halfway through his senior year of high school, a witty, introspective teen struggles to keep it a secret while falling in love with a brilliant classmate who inspires him to open his heart and not be defined by his condition.

Punk-rocker turned suburban mom, Kelly, is nostalgic for a life she can no longer have and uncertain of a future she doesn’t yet fit in. Seventeen-year-old Cal is frustrated at his lack of control over the hand he's been dealt. When the two strike up an unlikely friendship, it's the perfect spark needed to thrust them both back to life.