A poet falls in love with an art student, who gravitates to his bohemian lifestyle — and his love of heroin. Hooked as much on one another as they are on the drug, their relationship alternates between states of oblivion, self-destruction, and despair.

On his wedding day, Joseph nervously admits that his wife is not quite like other women. But his beautiful bride is more than just the "impulsive, compulsive, obsessive" woman he thinks he knows. And when Joseph discovers she is hiding troubling secrets, it sends them both on a sexual odyssey that will either destroy or redeem their relationship.

A gallerist risks her family and flourishing career when she enters into an affair with a talented painter and slowly loses control of her life.

Jody Balaban, an aspiring filmmaker, is fresh to L.A. with New York film school accolades and the dream of making her movie. Unable to get a job where she can use the skills she so finely honed, Jody must edit adult entertainment to make ends meet. The uncompromising desire to make her movie, leads Jody to secretly film in the porn studio facilities at night - until she is caught in the act.

A group of people awaken to find themselves prisoners in a mysterious house with no means of escape. They are each outfitted with electronic devices attached to the base of their skulls. The chemicals that the brain produces when in pain are collected by the devices, and when it collects a predetermined amount, the doors will be opened. In order to escape, they must hurt themselves and each other.

When Syd, a young editor at an influential art magazine, becomes involved with her neighbor, a drug-addicted lesbian photographer, both seek to exploit each other for their respective careers while slowly falling in love with each other.

A mind-bending love story following Greg who, after recently being divorced and then fired, meets the mysterious Isabel, a woman living on the streets and convinced that the polluted, broken world around them is just a computer simulation. Doubtful at first, Greg eventually discovers there may be some truth to Isabel’s wild conspiracy.

A young designer falls under a man's erotic spell and is drawn into a world of sexual abandon from which she may never return.

Trapped on her family’s isolated farm, Pearl must tend to her ailing father under the bitter and overbearing watch of her devout mother. Lusting for a glamorous life like she’s seen in the movies, Pearl’s ambitions, temptations, and repressions collide.

A teenager stops off to see his dealer to test a new drug before heading off for a night of partying. On the way home, he picks up an injured woman, and the night takes a surreal turn.

Over the course of three days Ross, a college dropout addicted to crystal-meth, encounters a variety of oddball folks - including a stripper named Nikki and her boyfriend, the local meth producer, The Cook - but all he really wants to do is hook up with his old girlfriend, Amy.

Ellie Parker, an aspiring actress from Australia, lives a hectic Hollywood lifestyle, perpetually trying to land the role that will elevate her career. Living with her lothario musician boyfriend, Justin, Ellie is far from happy, finding support primarily from her friend Sam. But when Ellie meets Chris after a minor traffic accident, she sees new potential for both romance and her life in general.

In a desolate community full of drug-addled Marines and rumors of kidnapping, a wild-eyed stoner named Lou wakes up after a crazy night of partying with symptoms of a strange illness and recurring visions. As she struggles to get a grip on reality, the stories of conspiracy spread.

Two drug dealers on the lam seek refuge inside their mentally unstable friend’s mansion. But in order to stay, they have to participate in her elaborate, and increasingly dangerous, game of permanent make-believe.

Utah and his girlfriend Opal, are drug addicts living on the streets in rural Ohio. After getting recruited by body broker Wood and offered treatment in Los Angeles, Wood takes Utah under his wing and introduces him to treatment center mogul Vin. Wood and Vin bring Utah in on their lucrative and illegal dealings, where saving lives comes second to the bottom line.

A bigoted junkie cop suffering from borderline personality disorder and drug addiction manipulates and hallucinates his way in a bid to secure promotion.

When aspiring model Jesse moves to Los Angeles, her youth and vitality are devoured by a group of beauty-obsessed women who will take any means necessary to get what she has.

In a town of low-income and fractured families, a group of teens are lured into working for a dangerous drug dealer. A new girl arrives who hides a dangerous secret that will impact everybody and change their lives forever.

A vampiric doctoral student tries to follow the philosophy of a nocturnal comrade and control her thirst for blood.

Sweet suburban teen Amanda is introduced by her new friends to prescription drug-sharing, but the recreational fun soon leads her to a life-altering heroin addiction.

A self-destructive punk rocker struggles with sobriety while trying to recapture the creative inspiration that led her band to success.

35-year-old Morris Bliss is clamped in the jaws of New York City inertia: he wants to travel but has no money, he needs a job but has no prospects, he still shares an apartment with his widowed father, and the premature death of his mother has left him emotionally walled up. When he finds himself wrapped up in an awkward relationship with Stephanie, the 18-year-old daughter of a former classmate, Morris quickly discovers his static life unraveling and opening up in ways that are long overdue.

The drug-induced utopias of four Coney Island residents are shattered when their addictions run deep.

An ophthalmologist's assistant with an unhealthy interest in human eyeballs goes on a killing spree to collect eyeballs for his overbearing mother's collection. Reality soon takes a bizarre turn, both for the characters and the audience.

Malcom's done with his life. Only the noise of Crystal Meth gives him a reason to keep going - everything else it has long regardless. Equipped with a bag full of weapons and self-made bombs, he makes his way to the nearby mall to really stir things up. On his personal war campaign, he not only changes his life radically, but also the fate of other people who are in the wrong place at the same time: a teenager whose favorite pastime is smoking pot in his dreary existence, a housewife, where their best days have been left behind, a greedy businessman whose only desire is to increase his wealth and a depressed pervert.

Forced to work extremely hard to keep things afloat, Paul begins hearing voices in his head questioning his past choices. Convinced that his wife has been unfaithful, he begins to see every male guest as a potential threat. What follows is Paul's downward spiral into the madness of deranged jealousy where he finally discovers that hell is not a state of mind – hell is himself.

Theresa, a haunted young woman spiraling in the wake of profound loss, is torn between her fractured emotional state and the reality-altering effects of a potent cannabinoid drug.

A young Romanian woman and a recovering drug addict launch an unlikely investigation after her parents are murdered by a vicious serial killer known as The Headhunter.

A small, seemingly innocuous plastic reel of film leads surveillance specialist Tom Welles down an increasingly dark and frightening path. With the help of the streetwise Max, he relentlessly follows a bizarre trail of evidence to determine the fate of a complete stranger. As his work turns into obsession, he drifts farther and farther away from his wife, family and simple life as a small-town PI.

The gruesome tapestry of psychological manifestations of a nineteen year old bulimic runaway stripper-turned prostitute as she descends into a hellish pit of satanic nightmares and hallucinations.

A young musician takes a beautiful tattoo artist on a ride in a stolen classic car.

Mabel Longhetti, desperate and lonely, is married to a Los Angeles municipal construction worker, Nick. Increasingly unstable, especially in the company of others, she craves happiness, but her extremely volatile behavior convinces Nick that she poses a danger to their family and decides to commit her to an institution for six months. Alone with a trio of kids to raise on his own, he awaits her return, which holds more than a few surprises.

An artist slowly goes insane while struggling to pay his bills, work on his paintings, and care for his two female roommates, which leads him taking to the streets of New York after dark and randomly killing derelicts with a power drill.

A suicidal artist goes into the desert, where he finds his doppelgänger, a homicidal drifter.

Ellie, a recovering drug addict, has just moved to a new city with her two teenage children. She has struggled to stay sober in the past and is determined to make it work this time, finding a stable job and regularly attending her meetings. Unfortunately, new friends, a new job, and the chance of a new life, can’t keep Ellie from slipping once again. Her life changes when she meets Christopher – a different kind of addict – which forces her daughter and son to accept a new version of Ellie.

Novella McClure is like most struggling actresses in Los Angeles: she's in her early 30s, her fake name sounded cooler ten years ago, and she hasn't landed a role in three years. To top it all off, she's developed a disturbing habit of eating her own flesh. Novella desperately tries to hide her strange condition from her motherly landlord, Eesha, and somewhat psychopathic best friend, Candice, but her body and mind continue to deteriorate in the depressing world of failed auditions and sketchy night clubs. Can a romantic relationship with her psychiatrist prevent her from self destruction? Or will her fatal habit continue to eat away at her?

A young drug addict who has lost touch with her rich family hits rock bottom when she sells her new-born baby to child traffickers. She soon regrets her decision and finds the courage and strength to get him back. To do so, she must follow a trail into the woods and find an eerie house where the old lady she met, her albino servant and a girl with a strange gait, all live together. Nothing could have prepared her for the horror she is about to discover.

As he helps a young artist with her upcoming exhibition, the owner of a mannequin shop's deadly, suppressed desires come to the surface.

A surrealistic anthology of horror films; four segments structured as an intense fever dream...

A young man turns from drug addiction and petty crime to a life redeemed by a discovery of compassion.

Lonely, unstable gas station attendant Melinda is tired of being overshadowed by her more confident, outgoing co-worker Sheila. When the gas station is held up at gunpoint by Billy, a desperate man in need of quick cash, Melinda finds an opportunity to make a connection with the robber, regardless of who gets hurt.

When a woman visits a Chinese doctor, she discovers her pain is due to pent-up rage, and the only cure is to fully express herself, whatever may come.

A young woman dealing with anorexia meets an unconventional doctor who challenges her to face her condition and embrace life.

Brian comes under the addictive spell of a parasite with the ability to induce euphoric hallucinations in its hosts.

Undercover cop Jim Raynor is a seasoned veteran. His partner, Kristen Cates, is lacking in experience, but he thinks she's tough enough to work his next case with him: a deep cover assignment to bring down the notoriously hard-to-capture drug lord Gaines. While their relationship turns romantic during the assignment, they also turn into junkies, and will have to battle their own addictions if they want to bring down Gaines once and for all.

Blonde Betty Elms has only just arrived in Hollywood to become a movie star when she meets an enigmatic brunette with amnesia. Meanwhile, as the two set off to solve the second woman's identity, filmmaker Adam Kesher runs into ominous trouble while casting his latest project.

A young heroin addict roams the streets of New York to panhandle and get her next fix, while her unstable boyfriend drifts in and out of her life at random.

A fading celebrity decides to use a black market drug, a cell-replicating substance that temporarily creates a younger, better version of herself.

A violent gang enlists the help of a hypnotherapist in an attempt to locate a painting which somehow vanished in the middle of a heist.

Sue Ann is a loner who keeps to herself in her quiet Ohio town. One day, she is asked by Maggie, a new teenager in town, to buy some booze for her and her friends, and Sue Ann sees the chance to make some unsuspecting, if younger, friends of her own.

A man on the verge of a promotion takes a mysterious hallucinogenic drug that begins to tear down his reality and expose his life for what it really is.

An artist dumps her longtime boyfriend, but her attempt to take a break from dating ends when she quickly finds herself in two passionate romances.

Lenny Brown moves to California to find his fortune in tax shelter investments. When the federal government changes the tax laws, poor Lenny finds himself $700,000 in hock with nowhere to turn. His friend, Joel, introduces him to cocaine to give Lenny that needed "boost". What ensues next is a descent into drug addiction and insanity as Lenny tries to regain control of his life, all the while needing that extra "boost".

An aimless adolescent joins several itinerant misfits who live on the fringe of society and welcome at-risk youths into their fold.

Driving cross-country, Ray and his wife and daughter stop at a highway rest area where his daughter falls and breaks her arm. After a frantic rush to the hospital and a clash with the check-in nurse, Ray is finally able to get her to a doctor. While the wife and daughter go downstairs for an MRI, Ray, exhausted, passes out in a chair in the lobby. Upon waking up, they have no record or knowledge of Ray's family ever being checked in.

After being stabbed with an ancient, germ-infested knife, a doctor finds himself with an insatiable desire for blood.

Barry is a drug-addled, abusive bastard who - after yet another bender - is abducted by aliens. Barry takes a backseat as an alien visitor assumes control of his body and takes it for a joyride through Cape Town. What follows is an onslaught of drugs, sex, and violence as our alien tourist enters the weird and wonderful world of humankind.

A clairvoyant therapist confronts her own personal demons while trying to save a young girl who believes a malevolent entity is feeding on her.

In the not-too-distant future, an all-seeing surveillance state conducts “dream audits” to collect taxes on the unconscious lives of the populace. Mild-mannered government agent James Preble travels to a remote farmhouse to audit the dreams of Arabella “Bella” Isadora, an eccentric, aging artist. Entering Bella’s vast VHS archive, which contains a lifetime of dreams, Preble stumbles upon a secret that offers him a chance at love—and hope for escape.

After kissing his wife and baby goodbye for a seemingly normal business trip, Reed checks himself into a hotel room to accomplish something he’s always dreamed of: the perfect murder. As his sinister plans unfold, he soon realizes he might be in over his head with a mysteriously unhinged call girl named Jackie.

Ken Park focuses on several teenagers and their tormented home lives. Shawn seems to be the most conventional. Tate is brimming with psychotic rage; Claude is habitually harassed by his brutish father and coddled, rather uncomfortably, by his enormously pregnant mother. Peaches looks after her devoutly religious father, but yearns for freedom. They're all rather tight, or so they claim.

José Sirgado is a low-budget filmmaker whose heroin addiction distorts his perspective of the real world. Although he is a depressed and unstable individual, his mood improves when he receives the mysterious films of Pedro, with whom he shares his passion for cinema.

A young woman, institutionalized by her abusive stepfather, retreats into a vivid fantasy world where she envisions a plan to escape. Gathering a group of fellow inmates, she embarks on a quest to collect five mystical items, blurring the lines between reality and imagination.

19 year old Linnéa leaves her small town in Sweden and heads for Los Angeles with the aim of becoming the world's next big porn star, but the road to her goal turns out to be bumpier than she imagined.

A German student, Stefan, now finished with his studies, hitchhikes to Paris. There he meets a free-spirited American girl, Estelle, who he follows to Ibiza. The two begin a sad and dark path into heroin addiction.

After a breakup, Wes ends up at a remote rest stop. He finds himself locked inside the bathroom with a mysterious figure speaking from an adjacent stall. Soon Wes realizes he is involved in a situation more terrible than he could imagine.

In Los Angeles, a colorful assortment of bohemians try to make sense of their intersecting lives. The moody Dark Smith, his bisexual girlfriend, her lesbian lover and their shy gay friend plan on attending the wildest party of the year. But they'll only make it if they can survive the drug trips, suicides, trysts, mutilations and alien abductions that occur as one surreal day unfolds.

After a painful breakup, Ben develops insomnia. To kill time, he starts working the late night shift at the local supermarket, where his artistic imagination runs wild.

A young Italian actress embarks on a self-destructive spree of sex, drugs and other excess while doing some soul searching to find the path for redemption.

When indie singer Grey struggles to write her sophomore album, she teams up with a mysterious producer at his secluded cabin. Though their bond strengthens her music, it also starts to irreparably alter Grey’s body and mind.

Traumatized since childhood by her brother's accidental death, Danika Merrick hallucinates a bank robbery and quits her job. Despite support from her three children and loving husband, Danika continues to experience unnerving visions. She seeks help from therapist Evelyn Harris but pervasive reports of violent incidents involving children make Danika fear for her own family, and she grows increasingly paranoid, worrying she may be going insane.

Aspiring actor Edward undergoes a radical medical procedure to drastically transform his appearance. But his new dream face quickly turns into a nightmare, as he loses out on the role he was born to play and becomes obsessed with reclaiming what was lost.

A young Los Angeles couple Tara and Sam fall head over heels into a new romance, entwining their lives—until their intimacy transforms into something terrifying.

When a dance troupe is lured to an empty school, a bowl of drug-laced sangria causes their jubilant rehearsal to descend into a dark and explosive nightmare as they try to survive the night—and find who's responsible—before it's too late.

A single mother and a childless morgue technician are bound together by their relationship to a little girl they have reanimated from the dead.

When Jane is rejected by life, she spirals into a chaotic, schizophrenic world where love and normality collide with humorous consequences.

A drug pusher grows increasingly desperate after a botched deal leaves him with a large debt to a ruthless drug lord.

A troubled actor, a television show runner, and an acclaimed videogame designer find their lives intertwining in mysterious and unsettling ways.

A New York film director, working on his latest movie in Los Angeles, begins to reflect the actions in his movie and real life, especially when he begins an affair with the lead actress.

A former circus artist escapes from a mental hospital to rejoin his armless, cult leader mother, and is forced to enact brutal murders in her name.

The story of a streetwise party girl who gets mixed up in a violent drug deal and finds a possible way out - by masquerading as a Catholic nun.

After getting into a serious car accident, a TV director discovers an underground sub-culture of scarred, omnisexual car-crash victims, and he begins to use car accidents and the raw sexual energy they produce to try to rejuvenate his sex life with his wife.

Dr. Hess Green becomes cursed by a mysterious ancient African artifact and is overwhelmed with a newfound thirst for blood. Soon after his transformation he enters into a dangerous romance with Ganja Hightower that questions the very nature of love, addiction, sex, and status.

A sex-addicted con-man pays for his mother's hospital bills by playing on the sympathies of those who rescue him from choking to death.

Carefree single guy Charlie Waters rooms with two lovely prostitutes, Barbara Miller and Susan Peters, and lives to gamble. Along with his glum betting buddy, Bill Denny, Charlie sets out on a gambling streak in search of the ever-elusive big payday. While Charlie and Bill have some lucky moments, they also have to contend with serious setbacks that threaten to derail their hedonistic betting binge.

Neto is a middle class teenager living a normal life. After his father finds a marijuana cigarette on his pocket, he is sent to a mental institution, where he gets to know a completely absurd and inhumane reality in which people are devoured by a corrupt and cruel system.

Ana, a teenager artist, is raised in Ibiza by her German father Klaus in a naturalist lifestyle. She meets Justine, who invites her to move to Madrid and get an artistic education and financial support. Ana befriends Linda, meets the problematic Said, a Saharawi youngster, and later she is hypnotized by Anglo, who opens a door to her memories and past lives.

An undercover cop in a not-too-distant future becomes involved with a dangerous new drug and begins to lose his own identity as a result.

After a friend overdoses, Spoon and Stretch decide to kick their drug habits and attempt to enroll in a government detox program. Their efforts are hampered by seemingly endless red tape, as they are shuffled from one office to another while being chased by drug dealers and the police.

A woman, accidentally caught in a dark deal, turns the tables on her captors and transforms into a merciless warrior evolved beyond human logic.

Friends become increasingly addicted to a video game that has an evil agenda.

A drama centered on a go-go dancer with multiple personality disorder who struggles to remain her true self and begins working with a psychotherapist to uncover the mystery of the inner ghosts that haunt her.

A young actress rehearsing for a play about human trafficking begins to relive terrifying scenes that may be dreams -- or an alternate reality.

After his wife leaves him, a disillusioned director dives into the drug scene, trying anything his friend suggests.

Laura Baxter is a young woman, literally a "sleeping beauty," who suffers from a medical condition called "parasomnia." A childhood accident victim, she is actually sleeping her life away, awakening briefly on rare occasions. Art student Danny Sloan falls in love with her, unaware that her hospital neighbor, a terrifying mass murderer and mesmerist named Byron Volpe has other, more sinister plans.

Madison is paralyzed by shocking visions of grisly murders, and her torment worsens as she discovers that these waking dreams are in fact terrifying realities with a mysterious tie to her past.

A drama centered on a troubled young woman who moves to San Francisco, where she gets involved in pornography and aligns herself with a cocaine-addicted lawyer.

A college freshman returns to Los Angeles for Christmas at his ex-girlfriend's request, but discovers that his former best friend has an out-of-control drug habit.

Three stories about the world of opioids collide: a drug trafficker arranges a multi-cartel Fentanyl smuggling operation between Canada and the U.S., an architect recovering from an OxyContin addiction tracks down the truth behind her son's involvement with narcotics, and a university professor battles unexpected revelations about his research employer, a drug company with deep government influence bringing a new "non-addictive" painkiller to market.