In need of creative inspiration, a professionally stagnant and hard-partying Los Angeles artist recklessly indulges in a series of drug binges. As the narcotics fly out of control, so does her newfound and inexplicable, yet unquenchable, craving for blood.

A young man turns from drug addiction and petty crime to a life redeemed by a discovery of compassion.

A German student, Stefan, now finished with his studies, hitchhikes to Paris. There he meets a free-spirited American girl, Estelle, who he follows to Ibiza. The two begin a sad and dark path into heroin addiction.

A college freshman returns to Los Angeles for Christmas at his ex-girlfriend's request, but discovers that his former best friend has an out-of-control drug habit.

Unable to cope with a recent personal tragedy, LA's top celebrity shrink turns into a pothead with no concern for his appearance and a creeping sense of his inability to help his patients.

The drug-induced utopias of four Coney Island residents are shattered when their addictions run deep.

A gallerist risks her family and flourishing career when she enters into an affair with a talented painter and slowly loses control of her life.

A shy but ambitious film student falls into an intense, emotionally fraught relationship with a charismatic but untrustworthy older man.

Teenagers Luke, Malachy, and Michelle embark on a wild weekend of drink, drugs, shop-lifting and stealing cars. But what starts out as a game turns deadly serious when the three discover that they can't get off the wild ride they've set in motion.

When Syd, a young editor at an influential art magazine, becomes involved with her neighbor, a drug-addicted lesbian photographer, both seek to exploit each other for their respective careers while slowly falling in love with each other.

A young heroin addict roams the streets of New York to panhandle and get her next fix, while her unstable boyfriend drifts in and out of her life at random.

Over the course of one night, a woman drives across LA with her heroin addict brother in search of a detox center, with his two-year-old daughter in tow.

Over the course of three days Ross, a college dropout addicted to crystal-meth, encounters a variety of oddball folks - including a stripper named Nikki and her boyfriend, the local meth producer, The Cook - but all he really wants to do is hook up with his old girlfriend, Amy.

Novella McClure is like most struggling actresses in Los Angeles: she's in her early 30s, her fake name sounded cooler ten years ago, and she hasn't landed a role in three years. To top it all off, she's developed a disturbing habit of eating her own flesh. Novella desperately tries to hide her strange condition from her motherly landlord, Eesha, and somewhat psychopathic best friend, Candice, but her body and mind continue to deteriorate in the depressing world of failed auditions and sketchy night clubs. Can a romantic relationship with her psychiatrist prevent her from self destruction? Or will her fatal habit continue to eat away at her?

A high school girl encounters a variety of kookie characters and humorous sexual situations while searching for the meaning of life.

A struggling painter is possessed by satanic forces after he and his young family move into their dream home in rural Texas.

The alienating and repetitive life of a group of heroin junkies in 1980s Rome.

A bigoted junkie cop suffering from borderline personality disorder and drug addiction manipulates and hallucinates his way in a bid to secure promotion.

Three stories about the world of opioids collide: a drug trafficker arranges a multi-cartel Fentanyl smuggling operation between Canada and the U.S., an architect recovering from an OxyContin addiction tracks down the truth behind her son's involvement with narcotics, and a university professor battles unexpected revelations about his research employer, a drug company with deep government influence bringing a new "non-addictive" painkiller to market.

Brandon, a thirty-something man living in New York, eludes intimacy with women but feeds his deepest desires with a compulsive addiction to sex. When his younger sister temporarily moves into his apartment, stirring up bitter memories of their shared painful past, Brandon's life, like his fragile mind, gets out of control.

Plagued by the abuse of her past and the turmoil of failed intimate encounters, Laura struggles to find a lover and a sense of normalcy. Her beacon of hope comes in sixteen year-old Eva, a talented pianist disillusioned by the life her mother imposes upon her. An unlikely relationship is formed between the two and Eva becomes an obsession to Laura. In light of Eva's unhappiness, Laura convinces her to runaway to her house and they soon find themselves caught within an intense entanglement. Manipulation, denial and codependency fuel what ultimately becomes a fractured dynamic that can only sustain itself for so long.

Humbert Humbert is a middle-aged British novelist who is both appalled by and attracted to the vulgarity of American culture. When he comes to stay at the boarding house run by Charlotte Haze, he soon becomes obsessed with Lolita, the woman's teenaged daughter.

The incredibly spoiled and overprivileged students of Camden College are a backdrop for an unusual love triangle between a drug dealer, a virgin and a bisexual classmate.

Heroin addict Mark Renton stumbles through bad ideas and sobriety attempts with his unreliable friends --Sick Boy, Begbie, Spud and Tommy. He also has an underage girlfriend, Diane, along for the ride. After cleaning up and moving from Edinburgh to London, Mark finds he can't escape the life he left behind as Begbie and Sick Boy come knocking.

Paul Rivers, an ailing mathematician lovelessly married to an English émigré; Christina Peck, an upper-middle-class suburban housewife and mother of two girls; and Jack Jordan, a born-again ex-con, are brought together by a terrible accident that changes their lives.

Cherry drifts from college dropout to army medic in Iraq—anchored only by his one true love, Emily. But after returning from the war with PTSD, his life spirals into drugs and crime as he struggles to find his place in the world.

The relationships of two couples become complicated and deceitful when the man from one couple meets the woman of the other.

When talented young writer Elizabeth Wurtzel earns a scholarship to Harvard, she sees it as her chance to escape the pressures of her working-class background and concentrate on her true talent. But what starts out so promising leads to self-destructive behavior and paralyzing depression that reflects an entire generation's struggle to navigate the effects of divorce, drugs, sex, and high expectations.

Ellie Parker, an aspiring actress from Australia, lives a hectic Hollywood lifestyle, perpetually trying to land the role that will elevate her career. Living with her lothario musician boyfriend, Justin, Ellie is far from happy, finding support primarily from her friend Sam. But when Ellie meets Chris after a minor traffic accident, she sees new potential for both romance and her life in general.

Poet/lecturer Charles Serking awakens from his alcoholic haze long enough to take a bus back to L.A. and plunge into an orgy of drink and sexual depravity.

Australian teenager Heidi is left with little choice but to leave home after she's caught red-handed with her mother's boyfriend. With few options, Heidi ends up in Jindabyne, a tourist community. Upon meeting Joe at a bar, she pursues a relationship with him and tries to find something resembling a normal home life. Heidi makes small strides by getting a job and finding a place to stay, but her relationship with Joe must overcome more than its share of hurdles.

Failed musician Jay abandoned his family and now earns a living as head bartender in a trendy London pub. Every Wednesday afternoon, a woman comes to his house for graphic, almost wordless, sex. One day, Jay follows her and learns about her. This eventually disrupts their relationship.

The son of a wealthy businessman finds solace in drugs and alcohol when he breaks up with his childhood love.

After a painful breakup, Ben develops insomnia. To kill time, he starts working the late night shift at the local supermarket, where his artistic imagination runs wild.

Hard-drinking novelist Zach Hutton spirals out of control after his wife and mistress both leave him. Alone and crippled by a bad case of writer's block, Zach slips in and out of casual relationships and one-night stands, while his drinking becomes more and more severe. With the help of a bartender and his therapist, Zach confronts his demons — women and alcohol.

George Orwell's novel of a totalitarian future society in which a man whose daily work is rewriting history tries to rebel by falling in love.

A story of a man who fakes his own death and assumes a new identity in order to escape his life, who then moves in with a woman who is also trying to leave her past behind.

Hayley’s a smart, charming teenage girl. Jeff’s a handsome, smooth fashion photographer. An Internet chat, a coffee shop meet-up, an impromptu fashion shoot back at Jeff’s place. Jeff thinks it’s his lucky night. He’s in for a surprise.

After his wife leaves him, a disillusioned director dives into the drug scene, trying anything his friend suggests.

The life of an unsuccessful writer is transformed by a top-secret 'smart drug' that allows him to use 100% of his brain and become a perfect version of himself. His enhanced abilities soon attract shadowy forces that threaten his new life.

Ken Park focuses on several teenagers and their tormented home lives. Shawn seems to be the most conventional. Tate is brimming with psychotic rage; Claude is habitually harassed by his brutish father and coddled, rather uncomfortably, by his enormously pregnant mother. Peaches looks after her devoutly religious father, but yearns for freedom. They're all rather tight, or so they claim.

In the late 1990s, up-and-coming mixed martial artist Mark Kerr aspires to become the greatest fighter in the world. However, he must also battle his opioid dependence and a volatile relationship with his girlfriend Dawn.

Kate and Charlie like to have a good time. Their marriage thrives on a shared fondness for music, laughter… and getting smashed. When Kate’s partying spirals into hard-core asocial behavior, compromising her job as an elementary schoolteacher, something’s got to give. But change isn’t exactly a cakewalk. Sobriety means she will have to confront the lies she’s been spinning at work, her troubling relationship with her mother, and the nature of her bond with Charlie.

After he and his first wife separate, journalist David Sheff struggles to help their teenage son, who goes from experimenting with drugs to becoming devastatingly addicted to methamphetamine.

The daughter of jazz pianist Joe Albany witnesses her beloved father's struggle -- and failure -- to kick his heroin habit.

After having visions of a member of her support group who killed herself, a woman who also suffers with chronic pain seeks out the widower of the suicide.

The story of a man who feels happy only when he is unhappy: addicted to sadness, with such need for pity, that he’s willing to do everything to evoke it from others. This is the life of a man in a world not cruel enough for him.

An undercover cop in a not-too-distant future becomes involved with a dangerous new drug and begins to lose his own identity as a result.

A brilliant but impulsive young surgeon spirals into self-destruction after a painful breakup, struggling to cope with love, loss, and the consequences of his own temper.

Theresa, a haunted young woman spiraling in the wake of profound loss, is torn between her fractured emotional state and the reality-altering effects of a potent cannabinoid drug.

Alex Linden is a psychiatrist living in Vienna who meets Milena Flaherty though a mutual friend. Though Alex is quite a bit older than Milena, he's attracted to her young, carefree spirit. Despite the fact that Milena is already married, their friendship quickly turns into a deeply passionate love affair that threatens to overtake them both. When Milena ends up in the hospital from an overdose, Alex is taken into custody by Inspector Netusil.

A reclusive English teacher suffering from severe obesity attempts to reconnect with his estranged teenage daughter for one last chance at redemption.

Dean and Cindy live a quiet life in a modest neighborhood. They appear to have the world at their feet at the outset of the relationship. However, his lack of ambition and her retreat into self-absorption cause potentially irreversible cracks in their marriage.

A top surgeon is besotted with a beautiful woman who once rebuffed him. Unable to come to terms with life without her, he tries to convince her that they need each other. She has other ideas, but a horrific accident leaves her at his mercy.

A disenfranchised 16-year-old girl connects to an older man on the internet and after a brief one-sided affair descends into obsession and anorexia.

A group of friends on holiday on an island experiment with a new designer drug that makes them lose their ability to control their urges.

Tom is a British chef in a Bondi restaurant who seems to have decided there are no longer any rules he needs to obey. Whatever Tom is up to, his actions seem to be tolerated by those around him. As Tom descends into darkness, fragments of a different story begin to emerge. All the women in his world are trying in their own, very different ways to help put him back together.

This movie portrays the drug scene in Berlin in the 70s, following tape recordings of Christiane F. 14 years old Christiane lives with her mother and little sister in a typical multi-storey apartment building in Berlin. She's fascinated by the 'Sound', a new disco with most modern equipment. Although she's legally too young, she asks a friend to take her. There she meets Detlef, who's in a clique where everybody's on drugs. Step by step she gets drawn deeper into the scene.

A recovering drug addict is granted a day’s leave from rehab and returns to Oslo, where he reconnects with friends, faces the weight of his past, and struggles with uncertainty about his future. Over the course of one day, he drifts through encounters that reflect his longing for connection and his deep sense of alienation.

A young Romanian woman and a recovering drug addict launch an unlikely investigation after her parents are murdered by a vicious serial killer known as The Headhunter.

A chronicle of three weeks in the lives of several high school teachers, administrators and students through the eyes of substitute teacher, Henry Barthes. Henry roams from school to school, imparting modes of knowledge, but never staying long enough to form any semblance of sentient attachment.

Best-selling author Tyvian Jones has a life of leisure in Venice, Italy, until he has a chance encounter with sultry Frenchwoman Eva Olivier. He falls for her instantly, despite already having wedding plans with Francesca Ferrara. Winning Eva's affection proves elusive; she's more interested in money than in love. But Tyvian remain steadfast in his obsession, going after Eva with a fervor that threatens to destroy his life.

After a friend overdoses, Spoon and Stretch decide to kick their drug habits and attempt to enroll in a government detox program. Their efforts are hampered by seemingly endless red tape, as they are shuffled from one office to another while being chased by drug dealers and the police.

Forced to move to a boring backwater town, a teenager embarks on affairs with a teacher and a stoner classmate.

Rock-and-roll singer Mary Rose Foster's romantic relationships and mental health are continuously imperilled by the demands of life on the road.

Following a breakdown and suicide attempt, an aging actor becomes involved with a much younger woman but soon finds that it's difficult to keep pace with her.

An aimless adolescent joins several itinerant misfits who live on the fringe of society and welcome at-risk youths into their fold.

A drama centered on a troubled young woman who moves to San Francisco, where she gets involved in pornography and aligns herself with a cocaine-addicted lawyer.

Jo, the mother of seven children, divorces her second husband in order to marry Jake, a successful but promiscuous screenwriter. Though they are physically and emotionally compatible, they are slowly torn apart.

Undercover cop Jim Raynor is a seasoned veteran. His partner, Kristen Cates, is lacking in experience, but he thinks she's tough enough to work his next case with him: a deep cover assignment to bring down the notoriously hard-to-capture drug lord Gaines. While their relationship turns romantic during the assignment, they also turn into junkies, and will have to battle their own addictions if they want to bring down Gaines once and for all.

Gifted but hot-headed sculptor Eric has a stormy, erotic, and star-crossed romance with a beautiful young woman named Olga.

Writer and Adderall enthusiast Stephen Elliott reaches a low point when his estranged father resurfaces, claiming that Stephen has fabricated much of the dark childhood that that fuels his writing. Adrift in the precarious gray area of memory, Stephen is led by three sources of inspiration: a new romance, the best friend who shares his history, and a murder trial that reminds him more than a little of his own story. Based on the memoir of the same name.

A young woman thinks she’s found a path to internet stardom when she starts making YouTube videos with a charismatic stranger – until the dark side of viral celebrity threatens to ruin them both.

Mabel Longhetti, desperate and lonely, is married to a Los Angeles municipal construction worker, Nick. Increasingly unstable, especially in the company of others, she craves happiness, but her extremely volatile behavior convinces Nick that she poses a danger to their family and decides to commit her to an institution for six months. Alone with a trio of kids to raise on his own, he awaits her return, which holds more than a few surprises.

Jack Manfred is an aspiring writer who to make ends meet, takes a job as a croupier. Jack remains an observer, knowing that everything in life is a gamble and that gamblers are born to lose. Inevitably, he gets sucked into the world of the casino which takes its toll on his relationships and the novel he is writing.

Despite his dedication to the junior-high students who fill his classroom, idealistic teacher Dan Dunne leads a secret life of addiction that the majority of his students will never know. But things change when a troubled student Drey makes a startling discovery of his secret life, causing a tenuous bond between the two that could either end disastrously or provide a catalyst of hope.

A young designer falls under a man's erotic spell and is drawn into a world of sexual abandon from which she may never return.

A strange and destructive relationship develops between a chef and her neighbor, a former child actress.

José Sirgado is a low-budget filmmaker whose heroin addiction distorts his perspective of the real world. Although he is a depressed and unstable individual, his mood improves when he receives the mysterious films of Pedro, with whom he shares his passion for cinema.

With the intention to break free from the strict familial restrictions, a suicidal young woman sets up a marriage of convenience with a forty-year-old addict, an act that will lead to an outburst of envious love.

A young singer/songwriter, despite being married, becomes involved with her new guitarist, who she soon discovers has a dark past and may be a danger to her and those close to her.

Sweet suburban teen Amanda is introduced by her new friends to prescription drug-sharing, but the recreational fun soon leads her to a life-altering heroin addiction.

Sam Ellis is a man on the rise — a hot-shot federal prosecutor on the cusp of a bright political future. But what was meant to be a one-time experience with an escort turns into a growing addiction — a new demon threatening to destroy his life, family, and career.

A fading celebrity decides to use a black market drug, a cell-replicating substance that temporarily creates a younger, better version of herself.

On his wedding day, Joseph nervously admits that his wife is not quite like other women. But his beautiful bride is more than just the "impulsive, compulsive, obsessive" woman he thinks he knows. And when Joseph discovers she is hiding troubling secrets, it sends them both on a sexual odyssey that will either destroy or redeem their relationship.

A teenager stops off to see his dealer to test a new drug before heading off for a night of partying. On the way home, he picks up an injured woman, and the night takes a surreal turn.

Set in the Little Saigon district outside of Sydney, a woman trying to escape her past becomes embroiled in a drug deal.

A disparate group of characters unknowingly bond by the sexual choices they make. Consumed by loneliness, a British businessman ponders a rendezvous with a prostitute. The businessman's wife prepares to call it quits with her younger lover. A Brazilian student breaks up with her boyfriend in London. A recovering alcoholic travels to Phoenix in search of his missing daughter. A paroled sex offender struggles to stay composed when propositioned in a Denver airport. A widower's religious devotion is put to a difficult test.

Bored with her marriage to burnt out poet turned corporate executive Thierry, Zandalee falls prey to an old friend of her husband, the manipulative and egotistical Johnny and becomes enmeshed in a sensual, passionate and destructive affair.

It's 1983, and hopeless junkie Dick gets an unwelcome visit from the past - his seriously sleazy former cellmate, Bug, to be precise. Bug requires a crash course in the 80s: different music, different drugs, and machines in walls that dispense money. The latter development gives Dick an idea.

Remy, a seemingly naive and devout young woman, finds herself cast out from her religious cult. With no place to turn, she immerses herself into the underground world of truck stop sex workers. Under the watchful eye of their matriarch and an enigmatic local lawman, Remy navigates between her strained belief system and the code to find her true calling in life.

College freshman Abby tries to distance herself from her dark past while resisting her attraction to bad boy Travis.

A young woman, institutionalized by her abusive stepfather, retreats into a vivid fantasy world where she envisions a plan to escape. Gathering a group of fellow inmates, she embarks on a quest to collect five mystical items, blurring the lines between reality and imagination.

A withdrawn young man, Leland Fitzgerald is imprisoned for the murder of a mentally disabled boy, who also happened to be the brother of his girlfriend, Becky. As the community struggles to deal with the killing, Pearl Madison, a teacher at the prison, decides to write about Leland's case. Meanwhile, others affected by the murder, including Becky and her sister, Julie, must contend with their own problems.

John LeTour is a recovering drug user who suffers insomnia and still deals to a high-end New York clientele, even though he’s trying to move on from the business. John’s professional midlife crisis becomes something more acute — and dangerous — when he re-encounters an old flame while a string of seemingly drug-related murders rocks the city.

An exploration of the United States of America's war on drugs from multiple perspectives. For the new head of the Office of National Drug Control Policy, the war becomes personal when he discovers his well-educated daughter is abusing cocaine within their comfortable suburban home. In Mexico, a flawed, but noble policeman agrees to testify against a powerful general in league with a cartel, and in San Diego, a drug kingpin's sheltered trophy wife must learn her husband's ruthless business after he is arrested, endangering her luxurious lifestyle.

A man named Seligman finds a fainted wounded woman in an alley and he brings her home. She tells him that her name is Joe and that she is nymphomaniac. Joe tells her life and sexual experiences with hundreds of men since she was a young teenager while Seligman tells about his hobbies, such as fly fishing, reading about Fibonacci numbers or listening to organ music.

A production company begins casting for its next feature, and an up-and-coming actress named Rose tries to manipulate her filmmaker boyfriend, Alex, into giving her a screen test. Alex's wife, Emma, knows about the affair and is considering divorce, while Rose's girlfriend secretly spies on her and attempts to sabotage the relationship. The four storylines in the film were each shot in one take and are shown simultaneously, each taking up a quarter of the screen.

A stark portrayal of life among a group of heroin addicts who hang out in Needle Park in New York City. Played against this setting is a low-key love story between Bobby, a young addict and small-time hustler, and Helen, a homeless girl who finds in her relationship with Bobby the stability she craves.